ABCB1 p.Val801Ser

Predicted by SNAP2: A: D (53%), C: N (66%), D: D (80%), E: D (75%), F: D (63%), G: D (71%), H: D (75%), I: N (97%), K: D (80%), L: N (87%), M: N (93%), N: D (66%), P: D (71%), Q: D (63%), R: D (75%), S: D (66%), T: D (63%), W: D (80%), Y: D (75%),
Predicted by PROVEAN: A: D, C: D, D: D, E: D, F: N, G: D, H: D, I: N, K: D, L: N, M: N, N: D, P: D, Q: D, R: D, S: D, T: D, W: D, Y: D,

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[hide] Loo TW, Clarke DM
Locking intracellular helices 2 and 3 together inactivates human P-glycoprotein.
J Biol Chem. 2014 Jan 3;289(1):229-36. doi: 10.1074/jbc.M113.527804. Epub 2013 Nov 25., [PMID:24275649] [PubMed]

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[hide] Brewer FK, Follit CA, Vogel PD, Wise JG
In silico screening for inhibitors of p-glycoprotein that target the nucleotide binding domains.
Mol Pharmacol. 2014 Dec;86(6):716-26. doi: 10.1124/mol.114.095414. Epub 2014 Sep 30., [PMID:25270578] [PubMed]

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