ABCC8 p.Thr200Ala
| Predicted by SNAP2: | A: N (78%), C: N (72%), D: N (72%), E: N (78%), F: N (61%), G: N (78%), H: N (93%), I: N (78%), K: N (87%), L: N (78%), M: N (61%), N: N (93%), P: N (87%), Q: N (82%), R: N (82%), S: N (97%), V: N (82%), W: N (61%), Y: N (57%), |
| Predicted by PROVEAN: | A: N, C: N, D: N, E: N, F: N, G: N, H: N, I: N, K: N, L: N, M: N, N: N, P: N, Q: N, R: N, S: N, V: N, W: N, Y: N, |
[switch to compact view]
Comments [show]
None has been submitted yet.
[hide] HIV type 1 diversity in France, 1999-2001: molecul... AIDS Res Hum Retroviruses. 2003 Jan 1;19(1):41-7. Fleury H, Recordon-Pinson P, Caumont A, Faure M, Roques P, Plantier JC, Couturier E, Dormont D, Masquelier B, Simon F
HIV type 1 diversity in France, 1999-2001: molecular characterization of non-B HIV type 1 subtypes and potential impact on susceptibility to antiretroviral drugs.
AIDS Res Hum Retroviruses. 2003 Jan 1;19(1):41-7., [PMID:12596719]
Abstract [show]
Non-B HIV-1 samples collected in France between 1999 and 2001 were sequenced in the env, reverse transcriptase (RT), and protease genes (1) to characterize further the non-B strains circulating in the country, (2) to assess the importance of recombination, and (3) to describe the polymorphism of RT and protease genes and appreciate a possible impact on susceptibility to antiretroviral (ARV) drugs. The results show that, within a background of CRF02_AG predominance, there is a high genetic diversity of non-B isolates, including intersubtype recombinants. There is an extensive polymorphism of protease and RT genes compared with B consensus sequences; we have so far no data indicating that these non-B isolates may have reduced sensitivity to ARV drugs.
Comments [show]
None has been submitted yet.
No. Sentence Comment
35 The following polymorphisms were noted in a significant number of the samples: V35T, E36D, E122K, D123E, I135V/T, S162A/E, K173T, Q174K, D177E, I178M, T200A, Q207E, and R211E.
X
ABCC8 p.Thr200Ala 12596719:35:151
status: NEW