ABCC8 p.Glu203Ala
| Predicted by SNAP2: | A: N (66%), C: N (61%), D: N (87%), F: N (57%), G: N (66%), H: N (66%), I: D (53%), K: N (78%), L: D (53%), M: D (53%), N: N (78%), P: N (66%), Q: N (87%), R: N (82%), S: N (78%), T: N (78%), V: N (66%), W: D (59%), Y: N (57%), |
| Predicted by PROVEAN: | A: N, C: D, D: N, F: D, G: N, H: N, I: D, K: N, L: D, M: N, N: N, P: N, Q: N, R: N, S: N, T: N, V: D, W: D, Y: D, |
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[hide] Anion channels/transporters in plants: from molecu... Annu Rev Plant Biol. 2011 Jun;62:25-51. Barbier-Brygoo H, De Angeli A, Filleur S, Frachisse JM, Gambale F, Thomine S, Wege S
Anion channels/transporters in plants: from molecular bases to regulatory networks.
Annu Rev Plant Biol. 2011 Jun;62:25-51., [PMID:21275645]
Abstract [show]
Anion channels/transporters are key to a wide spectrum of physiological functions in plants, such as osmoregulation, cell signaling, plant nutrition and compartmentalization of metabolites, and metal tolerance. The recent identification of gene families encoding some of these transport systems opened the way for gene expression studies, structure-function analyses of the corresponding proteins, and functional genomics approaches toward further understanding of their integrated roles in planta. This review, based on a few selected examples, illustrates that the members of a given gene family exhibit a diversity of substrate specificity, regulation, and intracellular localization, and are involved in a wide range of physiological functions. It also shows that post-translational modifications of transport proteins play a key role in the regulation of anion transport activity. Key questions arising from the increasing complexity of networks controlling anion transport in plant cells (the existence of redundancy, cross talk, and coordination between various pathways and compartments) are also addressed.
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No. Sentence Comment
367 Nevertheless, in contrast with human CLCs, AtCLCa anion selectivity is affected by the E203A mutation, resulting in a higher conductivity for chloride than for nitrate.
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ABCC8 p.Glu203Ala 21275645:367:87
status: NEW