ABCC8 p.Arg74Ala

Predicted by SNAP2: A: N (53%), C: D (63%), D: D (80%), E: N (53%), F: D (63%), G: D (95%), H: N (82%), I: N (57%), K: N (87%), L: N (78%), M: N (57%), N: N (61%), P: N (53%), Q: N (66%), S: N (61%), T: N (61%), V: N (57%), W: D (91%), Y: D (75%),
Predicted by PROVEAN: A: D, C: D, D: D, E: D, F: D, G: D, H: D, I: D, K: N, L: D, M: D, N: D, P: D, Q: D, S: D, T: D, V: D, W: D, Y: D,

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[hide] Pratt EB, Tewson P, Bruederle CE, Skach WR, Shyng SL
N-terminal transmembrane domain of SUR1 controls gating of Kir6.2 by modulating channel sensitivity to PIP2.
J Gen Physiol. 2011 Mar;137(3):299-314. Epub 2011 Feb 14., [PMID:21321069]

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