ABCB1 p.Trp232Ala

Predicted by SNAP2: A: D (53%), C: N (72%), D: D (75%), E: D (71%), F: N (66%), G: D (59%), H: D (53%), I: N (57%), K: D (75%), L: N (57%), M: N (82%), N: D (66%), P: D (85%), Q: D (66%), R: D (75%), S: D (53%), T: D (53%), V: N (57%), Y: N (72%),
Predicted by PROVEAN: A: D, C: D, D: D, E: D, F: D, G: D, H: D, I: D, K: D, L: D, M: D, N: D, P: D, Q: D, R: D, S: D, T: D, V: D, Y: D,

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[hide] Loo TW, Bartlett MC, Clarke DM
The W232R suppressor mutation promotes maturation of a truncation mutant lacking both nucleotide-binding domains and restores interdomain assembly and activity of P-glycoprotein processing mutants.
Biochemistry. 2011 Feb 8;50(5):672-85. Epub 2011 Jan 11., 2011-02-08 [PMID:21182301]

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