ABCB1 p.Ile59Arg

Predicted by SNAP2: A: N (87%), C: N (87%), D: D (75%), E: D (71%), F: N (87%), G: D (63%), H: D (66%), K: D (75%), L: N (97%), M: N (97%), N: D (71%), P: D (75%), Q: D (63%), R: D (71%), S: N (78%), T: N (82%), V: N (97%), W: D (71%), Y: D (66%),
Predicted by PROVEAN: A: N, C: D, D: D, E: D, F: N, G: D, H: D, K: D, L: N, M: N, N: D, P: D, Q: D, R: D, S: D, T: D, V: N, W: D, Y: D,

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[hide] Loo TW, Bartlett MC, Clarke DM
Arginines in the first transmembrane segment promote maturation of a P-glycoprotein processing mutant by hydrogen bond interactions with tyrosines in transmembrane segment 11.
J Biol Chem. 2008 Sep 5;283(36):24860-70. Epub 2008 Jul 2., 2008-09-05 [PMID:18596043]

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