ABCB1 p.Ala80Glu

Predicted by SNAP2: C: N (53%), D: D (71%), E: D (71%), F: D (59%), G: N (61%), H: D (66%), I: N (93%), K: D (66%), L: N (82%), M: D (59%), N: N (61%), P: D (75%), Q: N (57%), R: N (53%), S: N (87%), T: N (93%), V: N (97%), W: D (63%), Y: D (71%),
Predicted by PROVEAN: C: N, D: N, E: N, F: N, G: N, H: N, I: N, K: N, L: N, M: N, N: N, P: N, Q: N, R: N, S: N, T: N, V: N, W: D, Y: N,

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[hide] Sakurai A, Tamura A, Onishi Y, Ishikawa T
Genetic polymorphisms of ATP-binding cassette transporters ABCB1 and ABCG2: therapeutic implications.
Expert Opin Pharmacother. 2005 Nov;6(14):2455-73., [PMID:16259577]

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[hide] Zhou SF, Di YM, Chan E, Du YM, Chow VD, Xue CC, Lai X, Wang JC, Li CG, Tian M, Duan W
Clinical pharmacogenetics and potential application in personalized medicine.
Curr Drug Metab. 2008 Oct;9(8):738-84., [PMID:18855611]

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[hide] Mukonzo JK, Roshammar D, Waako P, Andersson M, Fukasawa T, Milani L, Svensson JO, Ogwal-Okeng J, Gustafsson LL, Aklillu E
A novel polymorphism in ABCB1 gene, CYP2B6*6 and sex predict single-dose efavirenz population pharmacokinetics in Ugandans.
Br J Clin Pharmacol. 2009 Nov;68(5):690-9., [PMID:19916993]

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[hide] Mukonzo JK, Waako P, Ogwal-Okeng J, Gustafsson LL, Aklillu E
Genetic variations in ABCB1 and CYP3A5 as well as sex influence quinine disposition among Ugandans.
Ther Drug Monit. 2010 Jun;32(3):346-52., [PMID:20357698]

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[hide] Grover S, Gourie-Devi M, Bala K, Sharma S, Kukreti R
Genetic association analysis of transporters identifies ABCC2 loci for seizure control in women with epilepsy on first-line antiepileptic drugs.
Pharmacogenet Genomics. 2012 Jun;22(6):447-65., [PMID:22565165]

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