ABCB1 p.Arg113Ala

Predicted by SNAP2: A: N (53%), C: D (71%), D: D (63%), E: N (53%), F: D (80%), G: N (53%), H: N (61%), I: D (63%), K: N (82%), L: D (63%), M: N (61%), N: N (61%), P: D (71%), Q: N (72%), S: N (72%), T: N (72%), V: D (59%), W: D (80%), Y: D (75%),
Predicted by PROVEAN: A: N, C: D, D: N, E: N, F: D, G: D, H: N, I: N, K: N, L: N, M: N, N: N, P: N, Q: N, S: N, T: N, V: N, W: D, Y: D,

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[hide] Loo TW, Clarke DM
The human multidrug resistance P-glycoprotein is inactive when its maturation is inhibited: potential for a role in cancer chemotherapy.
FASEB J. 1999 Oct;13(13):1724-32., [PMID:10506575]

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[hide] Loo TW, Clarke DM
Quality control by proteases in the endoplasmic reticulum. Removal of a protease-sensitive site enhances expression of human P-glycoprotein.
J Biol Chem. 1998 Dec 4;273(49):32373-6., 1998-12-04 [PMID:9829963]

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