ABCC1 p.Arg1249Asp

Predicted by SNAP2: A: D (85%), C: D (85%), D: D (95%), E: D (91%), F: D (85%), G: D (91%), H: D (80%), I: D (85%), K: D (80%), L: D (91%), M: D (80%), N: D (91%), P: D (91%), Q: D (66%), S: D (80%), T: D (91%), V: D (85%), W: D (91%), Y: D (91%),
Predicted by PROVEAN: A: D, C: D, D: D, E: D, F: D, G: D, H: D, I: D, K: D, L: D, M: D, N: D, P: D, Q: D, S: D, T: D, V: D, W: D, Y: D,

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[hide] Situ D, Haimeur A, Conseil G, Sparks KE, Zhang D, Deeley RG, Cole SP
Mutational analysis of ionizable residues proximal to the cytoplasmic interface of membrane spanning domain 3 of the multidrug resistance protein, MRP1 (ABCC1): glutamate 1204 is important for both the expression and catalytic activity of the transporter.
J Biol Chem. 2004 Sep 10;279(37):38871-80. Epub 2004 Jun 18., 2004-09-10 [PMID:15208328]

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