ABCC1 p.Lys1092Glu

Predicted by SNAP2: A: D (53%), C: D (63%), D: D (66%), E: D (71%), F: D (80%), G: D (63%), H: N (53%), I: D (63%), L: D (53%), M: D (59%), N: N (53%), P: D (75%), Q: N (61%), R: N (72%), S: N (53%), T: N (53%), V: D (63%), W: D (91%), Y: D (80%),
Predicted by PROVEAN: A: D, C: D, D: D, E: N, F: D, G: D, H: D, I: D, L: D, M: N, N: D, P: D, Q: N, R: N, S: N, T: D, V: D, W: D, Y: D,

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[hide] Zhang DW, Gu HM, Situ D, Haimeur A, Cole SP, Deeley RG
Functional importance of polar and charged amino acid residues in transmembrane helix 14 of multidrug resistance protein 1 (MRP1/ABCC1): identification of an aspartate residue critical for conversion from a high to low affinity substrate binding state.
J Biol Chem. 2003 Nov 14;278(46):46052-63. Epub 2003 Sep 3., 2003-11-14 [PMID:12954620]

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