ABCC1 p.Cys7Ala

Predicted by SNAP2: A: D (63%), D: D (85%), E: D (80%), F: D (80%), G: D (75%), H: D (71%), I: D (75%), K: D (85%), L: D (75%), M: D (80%), N: D (75%), P: D (91%), Q: D (80%), R: D (80%), S: D (66%), T: D (75%), V: D (75%), W: D (85%), Y: D (75%),
Predicted by PROVEAN: A: D, D: N, E: D, F: D, G: D, H: D, I: D, K: D, L: D, M: D, N: D, P: D, Q: D, R: D, S: D, T: D, V: D, W: D, Y: D,

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[hide] Yang Y, Chen Q, Zhang JT
Structural and functional consequences of mutating cysteine residues in the amino terminus of human multidrug resistance-associated protein 1.
J Biol Chem. 2002 Nov 15;277(46):44268-77. Epub 2002 Sep 13., 2002-11-15 [PMID:12235150]

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[hide] Leslie EM, Letourneau IJ, Deeley RG, Cole SP
Functional and structural consequences of cysteine substitutions in the NH2 proximal region of the human multidrug resistance protein 1 (MRP1/ABCC1).
Biochemistry. 2003 May 13;42(18):5214-24., 2003-05-13 [PMID:12731862]

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[hide] Ito K, Weigl KE, Deeley RG, Cole SP
Mutation of proline residues in the NH(2)-terminal region of the multidrug resistance protein, MRP1 (ABCC1): effects on protein expression, membrane localization, and transport function.
Biochim Biophys Acta. 2003 Sep 2;1615(1-2):103-14., [PMID:12948592]

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