ABCC1 p.Pro196Ala

Predicted by SNAP2: A: D (53%), C: N (61%), D: D (63%), E: D (66%), F: D (59%), G: D (59%), H: N (53%), I: D (53%), K: D (63%), L: D (63%), M: D (53%), N: N (53%), Q: N (53%), R: D (63%), S: N (57%), T: D (53%), V: D (63%), W: D (66%), Y: D (59%),
Predicted by PROVEAN: A: D, C: D, D: D, E: D, F: D, G: D, H: D, I: D, K: D, L: D, M: D, N: D, Q: D, R: D, S: D, T: D, V: D, W: D, Y: D,

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[hide] Ito K, Olsen SL, Qiu W, Deeley RG, Cole SP
Mutation of a single conserved tryptophan in multidrug resistance protein 1 (MRP1/ABCC1) results in loss of drug resistance and selective loss of organic anion transport.
J Biol Chem. 2001 May 11;276(19):15616-24. Epub 2001 Feb 21., 2001-05-11 [PMID:11278867]

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[hide] Ito K, Weigl KE, Deeley RG, Cole SP
Mutation of proline residues in the NH(2)-terminal region of the multidrug resistance protein, MRP1 (ABCC1): effects on protein expression, membrane localization, and transport function.
Biochim Biophys Acta. 2003 Sep 2;1615(1-2):103-14., [PMID:12948592]

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