ABCC7 p.Phe312Arg

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PMID: 24412276 [PubMed] Loo TW et al: "The cystic fibrosis V232D mutation inhibits CFTR maturation by disrupting a hydrophobic pocket rather than formation of aberrant interhelical hydrogen bonds."
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254 Accordingly, wild-type CFTR and mutants F229R, F236R, F310R, F312R, L346R, V350R and F354R were expressed in HEK 293 cells and whole cell SDS extracts were subjected to immunoblot analysis.
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ABCC7 p.Phe312Arg 24412276:254:61
status: NEW
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286 (A) Whole cell SDS extracts of cells expressing wild-type (WT), F229R, F236R, F310R, F312R, L346R, V350R and F354R CFTR mutants were subjected to immunoblot analysis.
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ABCC7 p.Phe312Arg 24412276:286:85
status: NEW
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