ABCC7 p.Ser1118Thr

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PMID: 23955087 [PubMed] Wang W et al: "Relative contribution of different transmembrane segments to the CFTR chloride channel pore."
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167 Block by intracellular Au(CN)2 - was also significantly weakened in S1118A, S1118T, and T1115A compared to wild type, especially at hyperpolarized membrane potentials (Fig. 6); however, no apparent "U"-shape to the fractional current-voltage relationship was observed (Fig. 6b).
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ABCC7 p.Ser1118Thr 23955087:167:76
status: NEW
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