ABCC7 p.Arg487Ala
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PMID: 11597353
[PubMed]
Boucherot A et al: "Role of CFTR's PDZ1-binding domain, NBF1 and Cl(-) conductance in inhibition of epithelial Na(+) channels in Xenopus oocytes."
No.
Sentence
Comment
171
We therefore introduced mutations into NBF1 sites which are essential for binding/hydrolysis of ATP and GTP and which have homology to GTP binding proteins such as Walker A (loop L1) (K464A, S466L), switch I motif (KH483/484AA, R487A), switch II motif (loop L4, G551D) and Walker B (D572N) [23].
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ABCC7 p.Arg487Ala 11597353:171:228
status: NEW