ABCC7 p.Phe1111Ser

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PMID: 10866956 [PubMed] Zhang ZR et al: "Interaction between permeation and gating in a putative pore domain mutant in the cystic fibrosis transmembrane conductance regulator."
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33 Preparation of oocytes and cRNA CFTR was subcloned into the pALTER vector (Promega), and the S1118F, S1118A, and S1118F/F1111S mutations were made using the Promega Altered Sites protocol (McDonough et al., 1994).
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ABCC7 p.Phe1111Ser 10866956:33:120
status: NEW
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118 To determine whether this imposed pattern was the source of relaxations in S1118F-CFTR, due to introduction of another bulky residue, the double mutation S1118F/F1111S was constructed.
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ABCC7 p.Phe1111Ser 10866956:118:161
status: NEW
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