ABCG2 p.Ser195Ala
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PMID: 26294421
[PubMed]
Haider AJ et al: "Identification of residues in ABCG2 affecting protein trafficking and drug transport, using co-evolutionary analysis of ABCG sequences."
No.
Sentence
Comment
109
We made individual substitutions of each amino acid to alanine: M131A, S195A, K453A, K473A, P485A, M549A, W564A and I573A.
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ABCG2 p.Ser195Ala 26294421:109:71
status: NEW153 Firstly, there was a group of five mutants which showed FTC-inhibited MX export comparable to WT protein (e.g. M131A, S195A, K453A, K473A, W564A; M131A data shown in Figure 3C).
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ABCG2 p.Ser195Ala 26294421:153:118
status: NEW