ABCG2 p.Arg191Gln
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PMID: 23800412
[PubMed]
Saranko H et al: "Effects of the gout-causing Q141K polymorphism and a CFTR DeltaF508 mimicking mutation on the processing and stability of the ABCG2 protein."
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Comment
20
http://dx.doi.org/10.1016/j.bbrc.2013.06.054 Abbreviations: CFTR, cystic fibrosis transmembrane conductance regulator, ABCC7; HEK, human embryonic kidney 293 cells; NBD, nucleotide binding domain; MBP, maltose binding protein; TMD, transmembrane domain; PBA, 4-phenylbutyrate; Sf9, Spodoptera frugiperda cells; SNP, single nucleotide polymorphism; 3R, G188E, R191Q, and R193K rescue mutations in ABCG2-NBD.
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ABCG2 p.Arg191Gln 23800412:20:359
status: NEW113 Therefore all these three mutations were introduced into the corresponding regions of the ABCG2 DF142 construct (3R: G188E, R191Q, and R193K).
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ABCG2 p.Arg191Gln 23800412:113:124
status: NEW