ABCB10 p.Arg691His
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PMID: 23716676
[PubMed]
Shintre CA et al: "Structures of ABCB10, a human ATP-binding cassette transporter in apo- and nucleotide-bound states."
No.
Sentence
Comment
129
The first construct used for crystallization had a PCR-derived mutation, which converted Arg691 to a histidine.
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ABCB10 p.Arg691His 23716676:129:89
status: NEW130 The R691H mutation led to a substantial loss of activity and ATPase activity was restored when the Arg691 was reintroduced (Fig. S6D).
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ABCB10 p.Arg691His 23716676:130:4
status: NEW