ABCB3 p.Ser251Cys
[switch to full view]Comments [show]
None has been submitted yet.
PMID: 26324772
[PubMed]
Geng J et al: "Use of Functional Polymorphisms To Elucidate the Peptide Binding Site of TAP Complexes."
No.
Sentence
Comment
228
We found that the TC2R peptide could be conjugated via BMOE only to rTAP1*(E436C)/TAP2a* but not to rTAP1*(S263C)/ TAP2a* or rTAP1*/TAP2a* (S251C) (Fig. 6B).
X
ABCB3 p.Ser251Cys 26324772:228:140
status: NEW232 In contrast, the lack of cross-linking of rTAP1*/TAP2a* (S251C) or rTAP1*(S263C)/TAP2a* mutants to TC2R could not be explained by the impaired binding of these mutants because transport and binding of the TR peptide by rTAP1/TAP2(S251A) and rTAP1(S263A)/TAP2 complexes were not reduced relative to the wild-type TAP (Supplemental Fig. 2).
X
ABCB3 p.Ser251Cys 26324772:232:57
status: NEW