ABCB3 p.Leu272Pro
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PMID: 24675550
[PubMed]
Forni D et al: "An evolutionary analysis of antigen processing and presentation across different timescales reveals pervasive selection."
No.
Sentence
Comment
288
Hap II carries the derived allele of rs3788524, which is an outlier in the YRI/AS FST distribution (Supplementary Figure S6); in AS and CEU this variant is in strong LD with L272P (rs2075939), which also defines HapII.
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ABCB3 p.Leu272Pro 24675550:288:174
status: NEW407 One nonsynonymous polymorphism (L272P) in NCF4, encoding a cytosolic regulatory component of the NADPH oxidase complex, was also identified as a possible balancing selection target in human populations.
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ABCB3 p.Leu272Pro 24675550:407:32
status: NEW