ABCB1 p.Tyr444Glu
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PMID: 25987565
[PubMed]
Loo TW et al: "The Transmission Interfaces Contribute Asymmetrically to the Assembly and Activity of Human P-glycoprotein."
No.
Sentence
Comment
199
All the Y444X mutants except Y444E differed from their Tyr-1087 counterparts as they yielded detectable levels of mature 170 kDa P-gp.
X
ABCB1 p.Tyr444Glu 25987565:199:29
status: NEW206 With the exception of Y444E, the Tyr-444 mutations had less severe effects on P-gp activity.
X
ABCB1 p.Tyr444Glu 25987565:206:22
status: NEW