ABCB1 p.Leu443*
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PMID: 25987565
[PubMed]
Loo TW et al: "The Transmission Interfaces Contribute Asymmetrically to the Assembly and Activity of Human P-glycoprotein."
No.
Sentence
Comment
174
Accordingly, A52-tagged mutants L443X (X afd; A, S, F, or R) were constructed.
X
ABCB1 p.Leu443* 25987565:174:32
status: NEW176 The amount of mature P-gp was then quantified. All of the L443X mutations had relatively minor effects on maturation of P-gp (Fig. 4A).
X
ABCB1 p.Leu443* 25987565:176:58
status: NEW179 Histidine-tagged versions of the L443X (X afd; A, S, F, or R) and F1086X (X afd; A, L, W, or R) mutants were expressed in HEK 293 cells in the presence of cyclosporine A to promote maturation of the mutants.
X
ABCB1 p.Leu443* 25987565:179:33
status: NEW