ABCB1 p.Asp164Gln
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PMID: 25533467
[PubMed]
Kluth M et al: "A mutation within the extended X loop abolished substrate-induced ATPase activity of the human liver ATP-binding cassette (ABC) transporter MDR3."
No.
Sentence
Comment
310
They demonstrated that the amino acid residue Gln-1175 of NBD2, which is identical to Gln-1174 in MDR3, hydrogen bonds with Asp-164 (Asp-166 in MDR3) of the ICL1 and identified this residue pair Asp-164-Gln-1175 as key residue pair in the transmission interface.
X
ABCB1 p.Asp164Gln 25533467:310:195
status: NEW309 They demonstrated that the amino acid residue Gln-1175 of NBD2, which is identical to Gln-1174 in MDR3, hydrogen bonds with Asp-164 (Asp-166 in MDR3) of the ICL1 and identified this residue pair Asp-164-Gln-1175 as key residue pair in the transmission interface.
X
ABCB1 p.Asp164Gln 25533467:309:195
status: NEW