ABCB1 p.Phe804Trp
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PMID: 24275649
[PubMed]
Loo TW et al: "Locking intracellular helices 2 and 3 together inactivates human P-glycoprotein."
No.
Sentence
Comment
108
Mature 170-kDa P-gp was the major product in mutants F804Y and F804W (Fig. 3, C and D), although the amount of mature protein in the absence of cyclosporine A in mutant F804W was lower than in F804Y (65% versus 85%, respectively).
X
ABCB1 p.Phe804Trp 24275649:108:63
status: NEWX
ABCB1 p.Phe804Trp 24275649:108:169
status: NEW