ABCB1 p.Leu258Ile
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PMID: 24275649
[PubMed]
Loo TW et al: "Locking intracellular helices 2 and 3 together inactivates human P-glycoprotein."
No.
Sentence
Comment
64
IH2-IH3 Cross-linking-Cysteine residues were introduced at each position within residues Leu258 to Ile-261 in IH2 and residues Trp803 and Phe804 in IH3 to generate eight different double cysteine mutants in a Cys-less background (40).
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ABCB1 p.Leu258Ile 24275649:64:89
status: NEW