ABCB1 p.Phe1086Trp
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PMID: 23733192
[PubMed]
Loo TW et al: "Human P-glycoprotein contains a greasy ball-and-socket joint at the second transmission interface."
No.
Sentence
Comment
176
By contrast, those containing mutations of hydrophobic residues (F1086Y, F1086L, or F1086W) did not inhibit maturation.
X
ABCB1 p.Phe1086Trp 23733192:176:84
status: NEW
PMID: 25987565
[PubMed]
Loo TW et al: "The Transmission Interfaces Contribute Asymmetrically to the Assembly and Activity of Human P-glycoprotein."
No.
Sentence
Comment
178
Mutants F1086A, F1086L, and F1086W yielded mature 170 kDa protein as the major product, whereas F1086R yielded little mature P-gp (b0d;5%) (Fig. 4A).
X
ABCB1 p.Phe1086Trp 25987565:178:28
status: NEW