ABCB1 p.Ser1077Gly
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PMID: 23733192
[PubMed]
Loo TW et al: "Human P-glycoprotein contains a greasy ball-and-socket joint at the second transmission interface."
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145
IH2 Mediates TMD/NBD Coupling in the P-gp Drug Pump JULY 12, 2013ߦVOLUME 288ߦNUMBER 28 JOURNAL OF BIOLOGICAL CHEMISTRY 20329 It is possible that mutations to Phe-1086 could affect ATP interactions because the residue is close to the Walker A site in NBD2 (residues Ser-1077 to Gly-1084).
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ABCB1 p.Ser1077Gly 23733192:145:278
status: NEW