ABCB1 p.Ala266Phe
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PMID: 23733192
[PubMed]
Loo TW et al: "Human P-glycoprotein contains a greasy ball-and-socket joint at the second transmission interface."
No.
Sentence
Comment
83
The double cysteine T333C/ L975C constructs (with or without the F1086A or A266F mutations) were transiently expressed in HEK 293 cells.
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ABCB1 p.Ala266Phe 23733192:83:75
status: NEW110 The Ala-266/Phe-1086 contact point appeared to be critical for function because mutant A266C/F1086C was inactive (21).
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ABCB1 p.Ala266Phe 23733192:110:4
status: NEW