ABCC7 p.Glu407Gln
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PMID: 8548288
[PubMed]
Sullivan SK et al: "Identification and partial characterization of a domain in CFTR that may bind cyclic nucleotides directly."
No.
Sentence
Comment
125
The current was only 18 + 13 % (n = 3) of wild-type level for the mutant channel with the glutamate at position 407 substituted by glutamine (mutant E407Q, using the single-letter amino-acid code); 16 + 3 % (n = 4) for the L408A mutant; and 17 ±+1 % (n = 4) for the T421A mutant (data not shown).
X
ABCC7 p.Glu407Gln 8548288:125:90
status: NEWX
ABCC7 p.Glu407Gln 8548288:125:149
status: NEW127 A double substitution mutant (E407Q plus E403D) produced 63 + 8 % (n = 9) wild-type channel current (wild-type =2250 + 195 nA; n = 5; data not shown).
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ABCC7 p.Glu407Gln 8548288:127:30
status: NEW124 The current was only 18 + 13 % (n = 3) of wild-type level for the mutant channel with the glutamate at position 407 substituted by glutamine (mutant E407Q, using the single-letter amino-acid code); 16 + 3 % (n = 4) for the L408A mutant; and 17 &#b1;+1 % (n = 4) for the T421A mutant (data not shown).
X
ABCC7 p.Glu407Gln 8548288:124:90
status: NEWX
ABCC7 p.Glu407Gln 8548288:124:149
status: NEW126 A double substitution mutant (E407Q plus E403D) produced 63 + 8 % (n = 9) wild-type channel current (wild-type =2250 + 195 nA; n = 5; data not shown).
X
ABCC7 p.Glu407Gln 8548288:126:30
status: NEW