ABCC7 p.Phe1450*
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PMID: 9325282
[PubMed]
Cotten JF et al: "Covalent modification of the regulatory domain irreversibly stimulates cystic fibrosis transmembrane conductance regulator."
No.
Sentence
Comment
80
NEM Stimulates in Part through R Domain Modification-To identify the cysteine(s) through which NEM was mediating its stimulatory effect, we examined the NEM response of CFTR variants in which individual or groups of cysteines were mutated to alanine(s) or deleted (F1450X deletes Cys1458 ).
X
ABCC7 p.Phe1450* 9325282:80:265
status: NEW124 Effect of NEM on CFTR containing cysteine to alanine mutations, on CFTR-⌬708-835, and on CFTR in which a portion of the C terminus has been deleted (F1450X).
X
ABCC7 p.Phe1450* 9325282:124:156
status: NEW81 NEM Stimulates in Part through R Domain Modification-To identify the cysteine(s) through which NEM was mediating its stimulatory effect, we examined the NEM response of CFTR variants in which individual or groups of cysteines were mutated to alanine(s) or deleted (F1450X deletes Cys1458 ).
X
ABCC7 p.Phe1450* 9325282:81:265
status: NEW125 Effect of NEM on CFTR containing cysteine to alanine mutations, on CFTR-D708-835, and on CFTR in which a portion of the C terminus has been deleted (F1450X).
X
ABCC7 p.Phe1450* 9325282:125:149
status: NEW