ABCC8 p.Thr338Ala
[switch to full view]Comments [show]
None has been submitted yet.
PMID: 11889571
[PubMed]
Gupta J et al: "Point mutations in the pore region directly or indirectly affect glibenclamide block of the CFTR chloride channel."
No.
Sentence
Comment
106
Two mutations in TM6, F337A and T338A, significantly weakened block by glibenclamide (Figs. 2, 3); this effect was apparently independent of the extracellu- 744 Fig. 5 Extracellular Cl-dependence of the apparent affinity and voltage dependence of glibenclamide block.
X
ABCC8 p.Thr338Ala 11889571:106:32
status: NEW