ABCC7 p.Ser877Cys
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PMID: 21746847
[PubMed]
Wang W et al: "Alignment of transmembrane regions in the cystic fibrosis transmembrane conductance regulator chloride channel pore."
No.
Sentence
Comment
265
Cysteine side chains can also be cross-linked between residues at the cytoplasmic ends of TM6 and TM12 (Chen et al., 2004), as well as between I340C (TM6) and S877C (TM7) (Wang et al., 2007); however, these findings are more difficult to interpret in structural terms because longer cross-linking molecules were used, and also because the side chain of I340C is not accessible to the aqueous lumen of the pore (Bai et al., 2010; El Hiani and Linsdell, 2010).
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ABCC7 p.Ser877Cys 21746847:265:159
status: NEW