ABCC7 p.Arg134Glu

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PMID: 22747419 [PubMed] Dalton J et al: "New Model of Cystic Fibrosis Transmembrane Conductance Regulator Proposes Active Channel-like Conformation."
No. Sentence Comment
131 Notably, a salt bridge between R134 and E1104 is supported by the finding that R134E/Q mutations are detrimental to channel Figure 8.
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ABCC7 p.Arg134Glu 22747419:131:79
status: NEW
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PMID: 26229102 [PubMed] Corradi V et al: "Cystic Fibrosis Transmembrane Conductance Regulator (CFTR): CLOSED AND OPEN STATE CHANNEL MODELS."
No. Sentence Comment
81 Additional distance restraints were also imposed to facilitate electrostatic interactions between residues (Arg-134-Glu-1104, Asp-873-Arg-933, and Arg-1102-Asp-1154) suggested to interact, based on the work of Dalton et al. (35).
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ABCC7 p.Arg134Glu 26229102:81:108
status: NEW
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