ABCC8 p.Glu1305Val

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PMID: 18450778 [PubMed] Dupuis JP et al: "Three C-terminal residues from the sulphonylurea receptor contribute to the functional coupling between the K(ATP) channel subunits SUR2A and Kir6.2."
No. Sentence Comment
53 The exact amino acid composition of SUR2A-MRP1 chimeric constructs and mutants were: S1M, SUR2A(M1-V1275) + MRP1(E1262-R1342) + SUR2A(M1358-K1545); S2M, SUR2A(M1-V1275) + MRP1(E1262-L1300) + SUR2A(R1316-K1545); S3M, SUR2A(M1-V1315) + MRP1(R1301-R1342) + SUR2A(M1358-K1545); S4M, SUR2A(M1-V1275) + MRP1(E1262-E1271) + SUR2A(S1286-K1545); S5M, SUR2A(M1-E1285) + MRP1(K1272-P1283) + SUR2A(P1299-K1545); S6M, SUR2A(M1-V1298) + MRP1(P1284-G1291) + SUR2A(E1307-K1545); S7M, SUR2A(M1-Q1304) + MRP1(V1290-L1300) + SUR2A(R1316-K1545); SUR2A(EIL/VFY), SUR2A with mutations E1305V, I1310F and L1313Y; S7M(VFY/EIL), S7M with mutations V1305E, F1310I and Y1313L; SUR2A(EIL/AAA), SUR2A with mutations E1305A, I1310A and L1313A.
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ABCC8 p.Glu1305Val 18450778:53:563
status: NEW
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