ABCB4 p.Ala364Thr
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PMID: 16505100
[PubMed]
Hari M et al: "Paclitaxel-resistant cells have a mutation in the paclitaxel-binding region of beta-tubulin (Asp26Glu) and less stable microtubules."
No.
Sentence
Comment
194
This has been observed in 1A9 cells made resistant to paclitaxel that harbor the mutation Phe270 Val or Ala364 Thr, where mutant tubulin mRNA is preferentially expressed.
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ABCB4 p.Ala364Thr 16505100:194:104
status: NEW