ABCB1 p.Leu553Pro
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PMID: 14645676
[PubMed]
Nakanishi T et al: "Functional characterization of human breast cancer resistance protein (BCRP, ABCG2) expressed in the oocytes of Xenopus laevis."
No.
Sentence
Comment
242
The latter is in agreement with previous observations of dominant-negative BCRP constructs possessing a mutation in the Walker A motif (K86M) (Ozvegy et al., 2002) or putative 5th transmembrane domain (L553P) (Kage et al., 2002), supporting the notion that the active form of BCRP is a homodimer.
X
ABCB1 p.Leu553Pro 14645676:242:202
status: NEW