ABCC2 p.Trp208Gly
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PMID: 15743976
[PubMed]
Vethanayagam RR et al: "Functional analysis of the human variants of breast cancer resistance protein: I206L, N590Y, and D620N."
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Sentence
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258
For instance, the W208G mutation located in the second extracellular loop of P-gp was shown to drastically reduce affinity of valinomysin, FK506, and ␣-factor for P-gp (Kwan and Gros, 1998).
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ABCC2 p.Trp208Gly 15743976:258:18
status: NEW