ABCC5 p.Arg1096Lys
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PMID: 16815813
[PubMed]
Choudhuri S et al: "Structure, function, expression, genomic organization, and single nucleotide polymorphisms of human ABCB1 (MDR1), ABCC (MRP), and ABCG2 (BCRP) efflux transporters."
No.
Sentence
Comment
467
Recently, Ito et al. (2001d) showed that in rat Mrp2, substitution of Arg at position 586 with Leu and Ile, and substitution of Arg at position 1096 with Lys, Leu, and Met, resulted in the acquisition of taurocholate transport activity, while retaining transport activity for glutathione and glucuronide conjugates.
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ABCC5 p.Arg1096Lys 16815813:467:128
status: NEW