ABCC11 p.Asn838Gln

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Publications
PMID: 19383836 [PubMed] Toyoda Y et al: "Earwax, osmidrosis, and breast cancer: why does one SNP (538G>A) in the human ABC transporter ABCC11 gene determine earwax type?"
No. Sentence Comment
73 The resulting expression construct [ABCC11 WT-pcDNA3.1/ Hygro(-)] was used as the template for site-directed mutagenesis to obtain ABCC11 variants, i.e., N838Q, N844Q, and N838Q/N844Q.
X
ABCC11 p.Asn838Gln 19383836:73:154
status: NEW
X
ABCC11 p.Asn838Gln 19383836:73:172
status: NEW
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75 To generate the N838Q/N844Q variant, ABCC11 N838Q- pcDNA3.1/Hygro(-) was used as the template.
X
ABCC11 p.Asn838Gln 19383836:75:16
status: NEW
X
ABCC11 p.Asn838Gln 19383836:75:44
status: NEW
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165 Substitution of both Asn838 and Asn844 to Gln residues completely diminished N-linked glycosylation of the ABCC11 WT (Fig. 5B), demonstrating that these two Asn residues are N-linked glycosylation sites in the ABCC11 WT protein.
X
ABCC11 p.Asn838Gln 19383836:165:21
status: NEW
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198 B) Effect of substitution of Asn838 and Asn844 to Gln on N-linked glycosylation status of ABCC11.
X
ABCC11 p.Asn838Gln 19383836:198:29
status: NEW
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74 The resulting expression construct [ABCC11 WT-pcDNA3.1/ Hygro(afa;)] was used as the template for site-directed mutagenesis to obtain ABCC11 variants, i.e., N838Q, N844Q, and N838Q/N844Q.
X
ABCC11 p.Asn838Gln 19383836:74:160
status: NEW
X
ABCC11 p.Asn838Gln 19383836:74:178
status: NEW
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76 To generate the N838Q/N844Q variant, ABCC11 N838Q- pcDNA3.1/Hygro(afa;) was used as the template.
X
ABCC11 p.Asn838Gln 19383836:76:16
status: NEW
X
ABCC11 p.Asn838Gln 19383836:76:44
status: NEW
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166 Substitution of both Asn838 and Asn844 to Gln residues completely diminished N-linked glycosylation of the ABCC11 WT (Fig. 5B), demonstrating that these two Asn residues are N-linked glycosylation sites in the ABCC11 WT protein.
X
ABCC11 p.Asn838Gln 19383836:166:21
status: NEW
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199 B) Effect of substitution of Asn838 and Asn844 to Gln on N-linked glycosylation status of ABCC11.
X
ABCC11 p.Asn838Gln 19383836:199:29
status: NEW
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