ABCC2 p.Phe368Ala
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PMID: 22542979
[PubMed]
Wittgen HG et al: "Phenylalanine 368 of multidrug resistance-associated protein 4 (MRP4/ABCC4) plays a crucial role in substrate-specific transport activity."
No.
Sentence
Comment
186
Mutation of Phe368 to Ala decreased transport of all substrates tested, whereas conservative substitutions with the aromatic Trp and Tyr residues caused substrate-dependent effects.
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ABCC2 p.Phe368Ala 22542979:186:12
status: NEW