ABCC4 p.Arg998Lys
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PMID: 18612080
[PubMed]
El-Sheikh AA et al: "Functional role of arginine 375 in transmembrane helix 6 of multidrug resistance protein 4 (MRP4/ABCC4)."
No.
Sentence
Comment
233
Glutamic acid (R998E) and lysine (R998K) mutants would be needed to strengthen this conclusion.
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ABCC4 p.Arg998Lys 18612080:233:34
status: NEW
PMID: 22542979
[PubMed]
Wittgen HG et al: "Phenylalanine 368 of multidrug resistance-associated protein 4 (MRP4/ABCC4) plays a crucial role in substrate-specific transport activity."
No.
Sentence
Comment
46
Site-directed mutagenesis of MRP4 and generation of expression vectors and baculovirus The previously described Gateway entry vector containing the human MRP4 coding sequence [8] was used as a template for site-directed mutagenesis of the following amino acids: F368W, F368Y, F368A, W995F, W995Y, W995A, R998S, R998K, R998Y, and R998L.
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ABCC4 p.Arg998Lys 22542979:46:311
status: NEW47 Site-directed mutagenesis of MRP4 and generation of expression vectors and baculovirus The previously described Gateway entry vector containing the human MRP4 coding sequence [8] was used as a template for site-directed mutagenesis of the following amino acids: F368W, F368Y, F368A, W995F, W995Y, W995A, R998S, R998K, R998Y, and R998L.
X
ABCC4 p.Arg998Lys 22542979:47:311
status: NEW