ABCA7 p.Gly1527Ala

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PMID: 22618995 [PubMed] Schellenberg GD et al: "The genetics and neuropathology of Alzheimer's disease."
No. Sentence Comment
274 This work also reported suggestive results for ABCA7 (5.0 9 10-7 , OR = 1.15, CI = 1.09-1.21) with the peak signal at a non-synonymous SNP that is potentially the pathogenic variant (p.Gly1527Ala).
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ABCA7 p.Gly1527Ala 22618995:274:185
status: NEW
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PMID: 26260791 [PubMed] Satoh K et al: "ATP-binding cassette transporter A7 (ABCA7) loss of function alters Alzheimer amyloid processing."
No. Sentence Comment
16 The single nucleotide polymorphisms (SNPs) associated with LOAD are distributed in various domains of the ABCA7 gene and include intronic SNPs and a coding sequence causing G1527A substitution.
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ABCA7 p.Gly1527Ala 26260791:16:173
status: NEW
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