ABCC8 p.Gly1342Ala

[switch to full view]
Comments [show]
Publications
PMID: 20103563 [PubMed] Klaassen CD et al: "Xenobiotic, bile acid, and cholesterol transporters: function and regulation."
No. Sentence Comment
6663 Nucleotide Change Amino Acid Change In Vitro Function Protein Expression/ Localization SLC22A6 OAT1 G149A R50H ↔ N.D. C311T P104L ↔ N.D. T677C I226T ↔ N.D. C767T A256V ↔ N.D. C877T R293W ↔ N.D. G1361A R454Q 2 N.D. SLC22A8 OAT3 C387A F129L ↔ N.D. C445A R149S 2 N.D. C715T Gln239STOP 2 N.D. T779G I260R 2 N.D. C829T R277W 2↔ N.D. T842C V281A ↔ N.D. A913T I305F 2 Normal C929T A310V ↔ N.D. G1195T A399S ↔ N.D. G1342A V448I ↔ N.D. 2, reduced function; ↔, no change in function; N.D. not determined.
X
ABCC8 p.Gly1342Ala 20103563:6663:477
status: NEW
Login to comment

6660 Nucleotide Change Amino Acid Change In Vitro Function Protein Expression/ Localization SLC22A6 OAT1 G149A R50H ࢒ N.D. C311T P104L ࢒ N.D. T677C I226T ࢒ N.D. C767T A256V ࢒ N.D. C877T R293W ࢒ N.D. G1361A R454Q 2 N.D. SLC22A8 OAT3 C387A F129L ࢒ N.D. C445A R149S 2 N.D. C715T Gln239STOP 2 N.D. T779G I260R 2 N.D. C829T R277W 2࢒ N.D. T842C V281A ࢒ N.D. A913T I305F 2 Normal C929T A310V ࢒ N.D. G1195T A399S ࢒ N.D. G1342A V448I ࢒ N.D. 2, reduced function; ࢒, no change in function; N.D. not determined.
X
ABCC8 p.Gly1342Ala 20103563:6660:467
status: NEW
Login to comment