ABCA1 p.Cys23Ala
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PMID: 21199866
[PubMed]
Fukuda Y et al: "Conserved intramolecular disulfide bond is critical to trafficking and fate of ATP-binding cassette (ABC) transporters ABCB6 and sulfonylurea receptor 1 (SUR1)/ABCC8."
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Comment
238
When the cysteines at ABCA1 residues 3 and 23 were substituted with alanine, confocal microscopic analysis showed that the mutant C3A/C23A-ABCA1 localized to both the plasma membrane and intracellular compartments (supplemental Fig. 5A).
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ABCA1 p.Cys23Ala 21199866:238:134
status: NEW