ABCC1 p.Tyr1267Trp
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PMID: 15542593
[PubMed]
Loo TW et al: "The dileucine motif at the COOH terminus of human multidrug resistance P-glycoprotein is important for folding but not activity."
No.
Sentence
Comment
109
Residue Leu1260 was mutated to Gly, Ile, Trp, Lys, or Glu, whereas residue Tyr1267 was mutated to Leu, Trp, Phe, or Lys.
X
ABCC1 p.Tyr1267Trp 15542593:109:75
status: NEW114 Mutants Y1267L, Y1267W, and Y1267F were still able to mature, because the major product was FIG. 2.
X
ABCC1 p.Tyr1267Trp 15542593:114:16
status: NEW