ABCA1 p.Leu162Val

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PMID: 11712864 [PubMed] Fruchart JC et al: "PPARS, metabolic disease and atherosclerosis."
No. Sentence Comment
88 Two polymorphisms were detected in PPAR-alpha gene, one in intron 3 and a missense mutation, leucine 162 to valine, in the DNA binding domain [41].
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ABCA1 p.Leu162Val 11712864:88:93
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94 In another recent report [42] association studies were undertaken in two populations of type 2 diabetic patients from Pondichery and from France [L162V (exon 5) and A268V (exon 7) polymorphisms].
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ABCA1 p.Leu162Val 11712864:94:146
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PMID: 19323963 [PubMed] Pearson ER et al: "Pharmacogenetics in diabetes."
No. Sentence Comment
140 In a study of another glitazar (dual-acting PPAR-γ/-α agonists), ragaglitazar, edema was less in those carrying the protective Ala allele at Pro12Ala PPAR-γ than the wild-type patients, and was not influenced by the Leu162Val SNP in PPAR-α [53].
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ABCA1 p.Leu162Val 19323963:140:234
status: NEW
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