ABCC8 p.Glu128Cys
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PMID: 21321069
[PubMed]
Pratt EB et al: "N-terminal transmembrane domain of SUR1 controls gating of Kir6.2 by modulating channel sensitivity to PIP2."
No.
Sentence
Comment
129
Bars: horizontal, 10 s; vertical, 1,000 pA for WT and E128C, and 200 pA for the rest.
X
ABCC8 p.Glu128Cys 21321069:129:54
status: NEW
PMID: 22802363
[PubMed]
Pratt EB et al: "Engineered interaction between SUR1 and Kir6.2 that enhances ATP sensitivity in KATP channels."
No.
Sentence
Comment
87
Fig. S5 illustrates that Q52C-Kir6.2//E128C-SUR1 channels show no evidence of cross-linking. Fig. S6 shows MgADP stimulation of Q52E-Kir6.2 channels.
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ABCC8 p.Glu128Cys 22802363:87:38
status: NEW206 However, no change in channel activity was observed in Q52C-Kir6.2//E128C-SUR1 than WT (Fig. 6), in contrast to the near 100-fold increase in ATP sensitivity observed in Q52E-Kir6.2// E203K-SUR1 (Fig. 2).
X
ABCC8 p.Glu128Cys 22802363:206:68
status: NEW