ABCC7 p.Ser809Arg

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PMID: 15910875 [PubMed] Matsuo M et al: "KATP channel interaction with adenine nucleotides."
No. Sentence Comment
184 Mutations within the ABC signature motif of NBF2 of SUR1 (S1482R) and SUR2B (S1446R) abolished the channel activation by MgADP, whereas the corresponding mutation of NBF1 of SUR1 (S830R) and SUR2B (S809R) did not [96].
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ABCC7 p.Ser809Arg 15910875:184:198
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187 Interestingly, the serine mutation of NBF1 (S809R) and NBF2 (S1446R) of SUR2A did not affect the channel activation by MgADP [96].
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ABCC7 p.Ser809Arg 15910875:187:44
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PMID: 12169627 [PubMed] Matsuo M et al: "Mutations in the linker domain of NBD2 of SUR inhibit transduction but not nucleotide binding."
No. Sentence Comment
238 We made the following mutations in the NBD1 linker: SUR1-S830R and SUR2-S809R (S1R); SUR1-Q774A, SUR1-H888A.
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ABCC7 p.Ser809Arg 12169627:238:72
status: NEW
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