ABCB1 p.Tyr114Cys
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PMID: 9829963
[PubMed]
Loo TW et al: "Quality control by proteases in the endoplasmic reticulum. Removal of a protease-sensitive site enhances expression of human P-glycoprotein."
No.
Sentence
Comment
79
Mutant Y114C showed reduced amounts of the 130-kDa product and increased amounts of core-glycosylated product.
X
ABCB1 p.Tyr114Cys 9829963:79:7
status: NEW107 Mutation of Tyr114 to Cys, Lys, Met, or Glu resulted in reduced amounts of 130-kDa product in the presence of MG-132.
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ABCB1 p.Tyr114Cys 9829963:107:12
status: NEW